3-Deazaneplanocin A
A lysine methyltransferase EZH2 (KMT63) inhibitor. DZNep is a selective inhibitor of trimethylation of lysine 27 on histone H3 (H3K27me3) and lysine 20 on histone H4 (H4K20me3). DZNep treatment of cultured human AML cells induces increased expression of the cell-cycle regulators p21, p27, and FBXO32, leading to cell cycle arrest and apoptosis.
Product Specifications
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
24 months
More Discoveries
Explore Other Products
Browse additional items from our catalog
034123-ML650 100 µL
COPZ2, CT (COPZ2, Coatomer subunit zeta-2, Zeta-2-coat protein) (MaxLight 650) discontinued
Sign In for Pricing
View Details TL712834V 500 µL Each
Cx3cl1 Rat shRNA Lentiviral Particle (Locus ID 89808)
Sign In for Pricing
View Details 
MBS1451004-01 0.02 mg (E-Coli)
Recombinant Vibrio parahaemolyticus Sulfurtransferase TusD homolog (tusD)
Sign In for Pricing
View Details MBS1451004-02 0.1 mg (E-Coli)
Recombinant Vibrio parahaemolyticus Sulfurtransferase TusD homolog (tusD)
Sign In for Pricing
View Details