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LDN-57444

Cell-permeable. LDN-57444 is a potent, reversible, competitive and active site-directed inhibitor of UCHL1 (Ki = 0.4 μM). Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis. Causes dramatic alterations in synaptic protein distribution and spine morphology in vivo.

Product Specifications

Shipping Conditions

gel pack

Storage Conditions

-20°C

Shelf Life

24months

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