Compound E
Cell-permeable. A potent, selective, non-transition state and non-competitive inhibitor of γ-secretase (IC₅₀ = 0.3 nM for total β-amyloid) and Notch processing. At higher concentrations (20-400 µM), only weakly affects the presenilase activity.
Product Specifications
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months
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CX335-C8-X 3 µm
Caprisil C8-X HPLC Column, 3 µm, 100 Å, CX535-C8-X x 125 mm
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