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Compound E

Cell-permeable. A potent, selective, non-transition state and non-competitive inhibitor of γ-secretase (IC₅₀ = 0.3 nM for total β-amyloid) and Notch processing. At higher concentrations (20-400 µM), only weakly affects the presenilase activity.

Product Specifications

Shipping Conditions

gel pack

Storage Conditions

-20°C

Shelf Life

36 months

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