3'-Azido-3'-deoxy-5-fluorocytidine
3'-Azido-3'-deoxy-5-fluorocytidine (Compound 12) is a cytidine derivative. 3'-Azido-3'-deoxy-5-fluorocytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
2095417-18-6
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology; Infection
Assay Protocol
https://www.medchemexpress.com/3_acute_-Azido-3_acute_-deoxy-5-fluorocytidine.html
Purity
99.90
Solubility
DMSO : 140 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@H](N=[N+]=[N-])[C@@H](CO)O[C@H]1N2C=C(F)C(N)=NC2=O
Molecular Formula
C9H11FN6O4
Molecular Weight
286.22
References & Citations
[1]Ren Hang, et al. Synthesis of 3'-Azido-D/L-nucleosides. Chinese Journal of Organic Chemistry, 2018, 38 (1) : 138-147.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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