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EZSolution™ L-685,458

Cell-permeable. A potent and selective γ-secretase inhibitor (IC₅₀ = 17 nM) .Displays > 50-fold selectivity over a range of aspartyl, serine and cysteine proteases. Exhibits equal potency for inhibition of Aβ40 and Aβ42 peptides (IC₅₀ values are 48 and 67 nM respectively in human neuroblastoma cells).

Product Specifications

Shipping Conditions

gel pack

Storage Conditions

-20°C

Shelf Life

24 months

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