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SIRT2 Inhibitor, AGK2

A potent inhibitor of sirtuin 2 (SIRT2) (IC₅₀ = 3.5 µM). AGK2 is >15-fold more selective for SIRT2 than SIRT1 and SIRt3. Inhibition of SIRT2 rescued α-synuclein toxicity and modified inclusion morphology in a cellular model of Parkinson’s disease.

Product Specifications

Shipping Conditions

RT

Storage Conditions

+4°C

Shelf Life

24 months

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