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VX-702

A p38 MAP kinase inhibitor. VX-702 dose-dependently inhibited the production of IL-6, IL-1β and TNFα (IC₅₀ = 59, 122 and 99 ng/ml, respectively). Pre-incubation of platelets with VX-702 (1 µM) completely or partially inhibited platelet agonist induced p38 activation (IC₅₀= 4 to 20 nM).

Product Specifications

Shipping Conditions

RT

Storage Conditions

-20°C

Shelf Life

24months

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