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5-Lipoxygenase Inhibitor Screening Kit (Fluorometric)

5-Lipoxygenase (5-LOX) is a non-heme iron-containing dioxygenase that converts unsaturated fatty acids to epoxides; for example the synthesis of leukotrienes from arachidonic acid. It is involved in processes like cell proliferation, differentiation and inflammation and has been implicated in inflammation and hyper proliferation mediated diseases like asthma, rheumatoid arthritis and cancer. Research for identifying potential remedies for such diseases involves the identification of inhibitors of 5-lipoxygenase. BioVision’s 5-Lipoxygenase Inhibitor Screening Kit uses Zileuton, a well-known 5-lipoxygenase inhibitor as positive control, and provides a simple and fast method to screen/ characterize potential 5-lipoxygenase inhibitors

Product Specifications

Reactivity

Human

Applications

Screening of potential inhibitors of 5-lipoxygenase

Detection Method

Fluorescence (Ex/Em 500/536 nm)

Features & Benefits

• Simple procedure; takes only ~40 min • Fast and convenient

Shipping Conditions

gel pack

Storage Conditions

-20°C

Shelf Life

12 months

Frequently Asked Questions

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