TNFSF18 (Human) ELISA Kit

Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1. Promotes leukocyte adhesion to endothelial cells. Regulates migration of monocytes from the splenic reservoir to sites of inflammation. BioVision’s TNFSF18 ELISA kit is a sandwich ELISA assay for the quantitative measurement of human TNFSF18 in serum, plasma and cell culture supernatants. The density of color is proportional to the amount of human TNFSF18 captured from the samples.