Hesperin

Hesperin is a bioactive ingredient present in Japanese horseradish (wasabi) and has been shown to be an Nrf2 activator.

Product Specifications

CAS Number

[4430-35-7]

UNSPSC

12352211

Hazard Statement

H302, H312, H332

Target

Keap1-Nrf2

Type

Reference compound

Related Pathways

NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Hesperin.html

Concentration

48.70 mM * 500 μL in Ethanol

Purity

99.20

Solubility

10 mM in DMSO|10 mM in Ethanol|10 mM in H2O

Smiles

O=S(CCCCCCN=C=S)C

Molecular Formula

C8H15NOS2

Molecular Weight

205.34

Precautions

H302, H312, H332

References & Citations

[1]Tanaka Y, et al. 6-Methylsulfinylhexyl isothiocyanate prevents high-fat diet-induced fatty liver but fails to attenuate hepatic iron accumulation in mice. Clin Exp Pharmacol Physiol. 2016 Nov;43 (11) :1153-1156.|[2]Okamoto T, et al. 6-Methylsulfinylhexyl isothiocyanate modulates endothelial cell function and suppresses leukocyte adhesion. J Nat Med. 2014 Jan;68 (1) :144-53.