Folylpolyglutamate Synthase (FPGS) (Human) ELISA Kit

Folylpolyglutamate synthase (FPGS) catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis. Unsubstituted reduced folates are the preferred substrates. Metabolizes methotrexate (MTX) to polyglutamates.. BioVision’s FPGS (Folic acid polyglutamate) ELISA kit is a sandwich ELISA assay for the quantitative measurement of FPGS in human serum, plasma and cell culture supernatants. The density of color is proportional to the amount of FPGS captured from the samples.