Digoxigenin NHS ester

Digoxigenin NHS ester is an activated ester which readily reacts with amino groups under mild conditions, attaching the Digoxigenin (HY-B1025) moiety to proteins or amino-. Digoxigenin NHS ester can be used to label proteins and oligonucleotides[1][2].

Product Specifications

CAS Number

[129273-26-3]

UNSPSC

12352005

Hazard Statement

H300+H310+H330, H373

Target

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/digoxigenin-nhs-ester.html

Purity

99.00

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@@]12[C@@]([C@@H](C(CO3)=CC3=O)CC1)([C@@H](C[C@@]4([H])[C@@]2([H])CC[C@@]5([H])[C@@]4(CC[C@@H](C5)OCC(NCCCCCC(ON6C(CCC6=O)=O)=O)=O)C)O)C

Molecular Formula

C35H50N2O10

Molecular Weight

658.78

Precautions

H300+H310+H330, H373

References & Citations

[1]Ulrich Brinkmann, et al. Covalently linked polypeptide toxin-antibody conjugates. Patent, WO2015101589A1.|[2]Dalia BURZYN, et al. Extracellular vesicle-aso constructs targeting stat6. Patent, WO2021030776A1.|[3]Graefe KA, et al. High-performance liquid chromatography with on-line post-column immunoreaction detection of digoxin and its metabolites based on fluorescence energy transfer in the far-red spectral region. J Chromatogr B Biomed Sci Appl. 2000 Aug 18;745 (2) :305-14.