CX516
CX516 (BDP 12) is an ampakine and acts as an AMPA receptor positive allosteric modulator for the research of Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI) [1].
Product Specifications
CAS Number
[154235-83-3]
Product Name Alternative
BDP 12
UNSPSC
12352005
Hazard Statement
H302
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Ampalex.html
Purity
99.94
Solubility
DMSO : 175 mg/mL (ultrasonic) |H2O : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(N1CCCCC1)C2=CC3=NC=CN=C3C=C2
Molecular Formula
C14H15N3O
Molecular Weight
241.29
Precautions
H302
References & Citations
[1]Broberg BV, Glenth?j BY, Dias R, et al. Reversal of cognitive deficits by an ampakine (CX516) and sertindole in two animal models of schizophrenia--sub-chronic and early postnatal PCP treatment in attentional set-shifting. Psychopharmacology (Berl) . 2009 Nov;206 (4) :631-40.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
AMPA Receptor
Available Sizes
Curated Selection
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