CX516
Product Specifications
UNSPSC Description
CX516 (BDP 12) is an ampakine and acts as an AMPA receptor positive allosteric modulator for the research of Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI)[1].
Target Antigen
iGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Ampalex.html
Purity
99.94
Solubility
DMSO : ≥ 41 mg/mL|H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(N1CCCCC1)C2=CC3=NC=CN=C3C=C2
Molecular Weight
241.29
References & Citations
[1]Broberg BV, Glenth?j BY, Dias R, et al. Reversal of cognitive deficits by an ampakine (CX516) and sertindole in two animal models of schizophrenia--sub-chronic and early postnatal PCP treatment in attentional set-shifting. Psychopharmacology (Berl). 2009 Nov;206(4):631-40.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-10933/CX516-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-10933/CX516-SDS-MedChemExpress.pdf
Clinical Information
Phase 3
CAS Number
154235-83-3
Available Sizes
Curated Selection
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