CX516

CX516 (BDP 12) is an ampakine and acts as an AMPA receptor positive allosteric modulator for the research of Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI) [1].

Product Specifications

CAS Number

[154235-83-3]

Product Name Alternative

BDP 12

UNSPSC

12352005

Hazard Statement

H302

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Ampalex.html

Purity

99.94

Solubility

DMSO : 175 mg/mL (ultrasonic) |H2O : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(N1CCCCC1)C2=CC3=NC=CN=C3C=C2

Molecular Formula

C14H15N3O

Molecular Weight

241.29

Precautions

H302

References & Citations

[1]Broberg BV, Glenth?j BY, Dias R, et al. Reversal of cognitive deficits by an ampakine (CX516) and sertindole in two animal models of schizophrenia--sub-chronic and early postnatal PCP treatment in attentional set-shifting. Psychopharmacology (Berl) . 2009 Nov;206 (4) :631-40.