Sortin1
Sortin1 is a vacuolar protein sorting inhibitor that targets carboxypeptidase Y (CPY) . Sortin1 is a soluble and membrane vacuolar marker molecule in plants and yeast[1].
Product Specifications
CAS Number
503837-98-7
UNSPSC
12352005
Target
Carboxypeptidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Sortin1.html
Concentration
10mM
Purity
99.54
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=C(C)NC2=C(C(C3=C2C=CC=C3)=O)C1C4=CC=C(C5=CC=C(C(O)=O)C=C5)O4)OC
Molecular Formula
C26H19NO6
Molecular Weight
441.43
References & Citations
[1]Zouhar J, et al. Sorting inhibitors (Sortins) : Chemical compounds to study vacuolar sorting in Arabidopsis. Proc Natl Acad Sci U S A. 2004 Jun 22;101 (25) :9497-501.|[2]Rosado A, et al. Sortin1-hypersensitive mutants link vacuolar-trafficking defects and flavonoid metabolism in Arabidopsis vegetative tissues. Chem Biol. 2011 Feb 25;18 (2) :187-97.|[3]Orr DJ, et al. 1H NMR-based metabolomics methods for chemical genomics experiments. Methods Mol Biol. 2014;1056:225-39.|[4]Vásquez-Soto B, et al. Sortin2 enhances endocytic trafficking towards the vacuole in Saccharomyces cerevisiae. Biol Res. 2015 Jul 25;48 (1) :39.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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