TNK-6123
Product Specifications
UNSPSC Description
TNK-6123 is a potent Emivirine (HY-15353) analogue with improved activity against drug-resistant HIV mutants. TNK-6123 improves activity against Lys103Asn mutant RT[1].
Target Antigen
Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/tnk-6123.html
Smiles
O=C1NC(C(C(C)C)=C(N1COCC)SC2CCCCC2)=O
Molecular Weight
326.45
References & Citations
[1]Hopkins AL, et al. Design of MKC-442 (emivirine) analogues with improved activity against drug-resistant HIV mutants. J Med Chem. 1999 Nov 4;42(22):4500-5.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-118731/TNK-6123-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-118731/
Clinical Information
No Development Reported
CAS Number
251481-69-3
Curated Selection
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