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TNK-6123

TNK-6123 is a potent Emivirine (HY-15353) analogue with improved activity against drug-resistant HIV mutants. TNK-6123 improves activity against Lys103Asn mutant RT[1].

Product Specifications

CAS Number

[251481-69-3]

UNSPSC

12352005

Target

Reverse Transcriptase

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/tnk-6123.html

Smiles

O=C1NC(C(C(C)C)=C(N1COCC)SC2CCCCC2)=O

Molecular Formula

C16H26N2O3S

Molecular Weight

326.45

References & Citations

[1]Hopkins AL, et al. Design of MKC-442 (emivirine) analogues with improved activity against drug-resistant HIV mutants. J Med Chem. 1999 Nov 4;42 (22) :4500-5.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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