TNK-6123
TNK-6123 is a potent Emivirine (HY-15353) analogue with improved activity against drug-resistant HIV mutants. TNK-6123 improves activity against Lys103Asn mutant RT[1].
Product Specifications
CAS Number
[251481-69-3]
UNSPSC
12352005
Target
Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/tnk-6123.html
Smiles
O=C1NC(C(C(C)C)=C(N1COCC)SC2CCCCC2)=O
Molecular Formula
C16H26N2O3S
Molecular Weight
326.45
References & Citations
[1]Hopkins AL, et al. Design of MKC-442 (emivirine) analogues with improved activity against drug-resistant HIV mutants. J Med Chem. 1999 Nov 4;42 (22) :4500-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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