Recombinant ODC1 Antibody / Ornithine Decarboxylase
Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1) . ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
Product Specifications
UniProt
P11926
Reactivity
Human
Immunogen
Recombinant human ODC-1 protein was used as the immunogen for this recombinant ODC1 antibody.
Clonality
Recombinant
Clone
ODC1/3636R
Conjugation
Unconjugated
Field of Research
Pharmacology & Drug Discovery
Purification
Protein A affinity chromatography
Dilution
Immunohistochemistry (FFPE) : 0.25-0.5ug/ml, Western blot: 0.5-1ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the recombinant ODC1 antibody should be determined by the researcher.
Tested Applications
IHC-P, WB
Host or Source
Rabbit
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Rabbit IgG, kappa
Frequently Asked Questions
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