Steviol
Steviol is the main metabolite of steviol glycosides and an inhibitor of AQP2/CFTR. Steviol slows down the growth of renal cysts by inhibiting the activity of CFTR, reducing the expression of AQP2, and promoting the degradation of AQP2 and CFTR. Steviol can be used in the research of polycystic kidney disease[1][2].
Product Specifications
CAS Number
471-80-7
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Aquaporin; CFTR; Chloride Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/steviol.html
Purity
99.85
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@@]1(C(O)=O)CCC[C@@]2(C)[C@@]3([H])[C@@]4(CC([C@@](CC3)(O)C4)=C)CC[C@]12[H]
Molecular Formula
C20H30O3
Molecular Weight
318.45
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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