(+) -Magnoflorine (chloride)

Magnoflorine chloride (Magnoflorine chloride), an aporphine alkaloid found in Magnolia or Aristolochia, reduces the formation of C. albicans biofilm[1]. Magnoflorine chloride has anti-fungal, anti-antidiabetic and anti-oxidative activity[2].

Product Specifications

CAS Number

[6681-18-1]

Product Name Alternative

Magnoflorine (chloride) ; α-Magnoflorine (chloride) ; Thalictrine (chloride)

UNSPSC

12352005

Hazard Statement

H302

Target

Fungal

Type

Natural Products

Related Pathways

Anti-infection

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/plus-magnoflorine-chloride.html

Purity

99.29

Solubility

H2O : 41.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC1=C(C2=C3O)C([C@]([N+]4(C)C)([H])CC2=CC=C3OC)=C(CC4)C=C1OC.[Cl-]

Molecular Formula

C20H24ClNO4

Molecular Weight

377.86

Precautions

H302

References & Citations

[1]Kim J, et al. Antifungal activity of magnoflorine against Candida strains. World J Microbiol Biotechnol. 2018 Oct 31;34 (11) :167.|[2]Haque MA, et al. Magnoflorine Enhances LPS-Activated Pro-Inflammatory Responses via MyD88-Dependent Pathways in U937 Macrophages. Planta Med. 2018 Nov;84 (17) :1255-1264.