AMPK activator 12
AMPK activator 12 (compound 21) is a potent AMPK activator and GDF15 inducer. AMPK activator 12 increases GDF15 protein levels in human hepatic cells[1].
Product Specifications
CAS Number
[431920-24-0]
UNSPSC
12352005
Target
AMPK
Type
Reference compound
Related Pathways
Epigenetics; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ampk-activator-12.html
Concentration
10mM
Purity
99.68
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
OC(CN(CC1=CC=CC=C1)CC2=CC=CC=C2)COC3=CC=C(Br)C=C3
Molecular Formula
C23H24BrNO2
Molecular Weight
426.35
References & Citations
[1]Meijian Zhang, et al. Design and Synthesis of AMPK Activators and GDF15 Inducers. Molecules. 2023 Jul 17;28 (14) :5468.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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