BAP1-IN-1
BAP1-IN-1 (Compound 8) is a BRCA1 associated protein 1 (BAP1) catalytic activity inhibitor with an IC50 of 0.1-1 μM[1].
Product Specifications
CAS Number
[353495-21-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bap1-in-1.html
Purity
99.86
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=[N+](C1=CC2=C(NC(C3=CC=CC=C3)C4C2C=CC4)C=C1)[O-]
Molecular Formula
C18H16N2O2
Molecular Weight
292.33
Precautions
H302, H315, H319
References & Citations
[1]Wang L, et al. Epigenetic targeted therapy of stabilized BAP1 in ASXL1 gain-of-function mutated leukemia. Nat Cancer. 2021 May;2 (5) :515-526.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1400310-01 0.02 mg (E-Coli)
Recombinant Xenopus laevis C-terminal-binding protein 2 (ctbp2)
Ask
View Details MBS1400310-02 0.02 mg (Yeast)
Recombinant Xenopus laevis C-terminal-binding protein 2 (ctbp2)
Ask
View Details MBS1400310-03 0.1 mg (E-Coli)
Recombinant Xenopus laevis C-terminal-binding protein 2 (ctbp2)
Ask
View Details 
MBS1400310-04 0.1 mg (Yeast)
Recombinant Xenopus laevis C-terminal-binding protein 2 (ctbp2)
Ask
View Details 
MBS1400310-05 0.02 mg (Baculovirus)
Recombinant Xenopus laevis C-terminal-binding protein 2 (ctbp2)
Ask
View Details