BAP1-IN-1
Product Specifications
UNSPSC Description
BAP1-IN-1 (Compound 8) is a BRCA1 associated protein 1 (BAP1) catalytic activity inhibitor with an IC50 of 0.1-1 μM[1].
Target Antigen
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bap1-in-1.html
Purity
99.83
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=[N+](C1=CC2=C(NC(C3=CC=CC=C3)C4C2C=CC4)C=C1)[O-]
Molecular Weight
292.33
References & Citations
[1]Wang L, et al. Epigenetic targeted therapy of stabilized BAP1 in ASXL1 gain-of-function mutated leukemia. Nat Cancer. 2021 May;2(5):515-526.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W327122/BAP1-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W327122/BAP1-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
353495-21-3
Available Sizes
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