Nav1.7 inhibitor
Nav1.7 inhibitor (compound II), a sulfonamide, is a potent Nav1.7 inhibitor. Nav1.7 inhibitor has the potential for a wide range of disorders, particularly pain, including acute pain, inflammatory pain and/or neuropathic pain[1].
Product Specifications
CAS Number
[1355631-24-1]
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Nav1.7-inhibitor.html
Concentration
10mM
Purity
99.63
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(NS(=O)(C)=O)C1=CC(Cl)=C(COC2=CC=C(Cl)C(Cl)=C2)C=C1F
Molecular Formula
C15H11Cl3FNO4S
Molecular Weight
426.67
References & Citations
[1]Alan Daniel Brown, et al. Preparation of sulfonamide derivatives as Nav1.7 inhibitors. Patent WO2012007868A2.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Nav1.7
Available Sizes
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