GFRA1/GDNFR-alpha-1, Canine (HEK293, His)
Product Specifications
UNSPSC Description
GFRA1 is a co-receptor that recognizes the GDNF ligand family and is involved in the regulation of proliferation, differentiation and migration of neuronal cells. GFRA1 promotes autophagy through the SRC-AMP-activated protein kinase (AMPK) signaling pathway, thereby contributing to the development of cisplatin-induced chemotherapy resistance to osteosarcoma. GFRA1/GDNFR-alpha-1 Protein, Canine (HEK293, His) is the recombinant canine-derived GFRA1/GDNFR-alpha-1 protein, expressed by HEK293 , with C-His labeled tag.
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/gfra1-gdnfr-alpha-1-protein-canine-hek293-his.html
Purity
98.0
Smiles
DRLDCVKASD QCLKEQSCST KYRTLRQCVA GKETNFSLTS GLEAKDECRS AMEALKQKSL YNCRCKRGMK KEKNCLRIYW SMYQSLQGND LLEDSPYEPV NSRLSDIFRV VPFLPDVLQQ VEHIPKGNNC LDAAKACNLD DTCKKYRSAY ITPCTTSMSN EVCNRRKCHK ALRQFFDKVP AKHSYGMLFC SCRDIACTER RRQTIVPVCS YEEREKPNCL NLQDSCKTNY ICRSRLADFF TNCQPESRSA SSCLKENYAD CLLAYSGLIG TVMTPNYIDS SSLSVAPWCD CSNSGNDLEE CLKFLNFFKD NTCLKNAIQA FGNGSDVTVW QPALPVQTTT ATTTTAFRAK NKPLGPAGSE NEIPTHVLPP CANLQAQKLK SNMSGSTHLC LSDRDYEKNG LSGPS
Molecular Weight
Approximately 53-60 kDa due to the glycosylation
Shipping Conditions
Blue Ice
Storage Conditions
Stored at -20°C for 2 years
Available Sizes
Curated Selection
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