Embusartan
Embusartan (BAY 10-6734) is a brain-penetrant and effective AT1 receptor blocker. Embusartan inhibits Ang II binding to brain AT1 receptors in the nuclei of central nervous system (CNS) inside due to high lipophilic character. Embusartan is promising for research of sympathetic hyperactivity and hypertension[1].
Product Specifications
CAS Number
156001-18-2
Product Name Alternative
BAY 10-6734
UNSPSC
12352005
Target
Angiotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/embusartan.html
Smiles
O=C(C(C=C(CCCC)N1CC2=CC=C(C3=CC=CC=C3C4=NN=NN4)C=C2F)=CC1=O)OC
Molecular Formula
C25H24FN5O3
Molecular Weight
461.49
References & Citations
[1]Wang JM, et al. Central nervous system blockade by peripheral administration of AT1 receptor blockers. J Cardiovasc Pharmacol. 2003 Apr;41 (4) :593-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
123751-AP 100 µL
ATR (Serine/Threonine-protein Kinase ATR, Ataxia Telangiectasia And Rad3-related Protein, FRAP-related Protein 1, FRP1) (AP) discontinued
Sign In for Pricing
View Details 
MBS7020120-01 0.02 mg
Recombinant Escherichia coli O8 Spermidine export protein MdtI (mdtI)
Sign In for Pricing
View Details MBS7020120-02 0.1 mg
Recombinant Escherichia coli O8 Spermidine export protein MdtI (mdtI)
Sign In for Pricing
View Details MBS7020120-03 5x 0.1 mg
Recombinant Escherichia coli O8 Spermidine export protein MdtI (mdtI)
Sign In for Pricing
View Details 
MBS1580436-01 0.1 mg
Research Grade Anti-Human CD121a/IL1R1 Antibody (AMG108)
Sign In for Pricing
View Details