SRA880 (free base)
SRA880 (free base) is a compound with antidepressant-modulating effects. It is a somatostatin-1 autoreceptor antagonist that can synergize with imipramine to produce antidepressant-like effects and affect BDNF mRNA expression and phosphorylation of related proteins.
Product Specifications
CAS Number
[187218-90-2]
UNSPSC
12352005
Target
Somatostatin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/sra880-free-base.html
Smiles
CN1[C@@]2([H])[C@@](C[C@H](C1)C(N3CCN(C4=CC=C(C=C4)[N+]([O-])=O)CC3)=O)([H])CC5=C(OC)C=CC=C5C2
Molecular Formula
C26H32N4O4
Molecular Weight
464.56
References & Citations
[1]Neuropeptidomics of mouse hypothalamus after imipramine treatment reveal somatostatin as a potential mediator of antidepressant effects
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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