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SRA880 (free base)

SRA880 (free base) is a compound with antidepressant-modulating effects. It is a somatostatin-1 autoreceptor antagonist that can synergize with imipramine to produce antidepressant-like effects and affect BDNF mRNA expression and phosphorylation of related proteins.

Product Specifications

CAS Number

[187218-90-2]

UNSPSC

12352005

Target

Somatostatin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/sra880-free-base.html

Smiles

CN1[C@@]2([H])[C@@](C[C@H](C1)C(N3CCN(C4=CC=C(C=C4)[N+]([O-])=O)CC3)=O)([H])CC5=C(OC)C=CC=C5C2

Molecular Formula

C26H32N4O4

Molecular Weight

464.56

References & Citations

[1]Neuropeptidomics of mouse hypothalamus after imipramine treatment reveal somatostatin as a potential mediator of antidepressant effects

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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