Anti-Mouse CD8 Antibody (HB-129)

Anti-Mouse CD8 Antibody (HB-129) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to mouse CD8. Anti-Mouse CD8 Antibody (HB-129) can deplete CD8+ T cells. Anti-Mouse CD8 Antibody (HB-129) can be used for the researches of cancer, inflammation, immunology and metabolic disease, such as P815 tumor, experimental autoimmune thyroiditis (EAT) and graft versus host disease (GVHD) [1][2][3].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352203

Target

Transmembrane Glycoprotein

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Field of Research

Cancer; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-cd8-antibody-hb-129.html

Purity

95.00

Solubility

10 mM in DMSO

Smiles

[Anti-MouseCD8Antibody(HB-129)]

Molecular Weight

(150 kDa)

References & Citations

[1]ang Y, et al. Antitumor T-cell responses contribute to the effects of dasatinib on c-KIT mutant murine mastocytoma and are potentiated by anti-OX40. Blood. 2012 Nov 29;120 (23) :4533-43.|[2]Tang H, et al. The kinetics of cytokine gene expression in the thyroids of mice developing granulomatous experimental autoimmune thyroiditis. J Autoimmun. 1998 Dec;11 (6) :581-9.|[3]Racine JJ, et al. Induction of mixed chimerism depletes pre-existing and de novo-developed autoreactive B cells in autoimmune NOD mice. Diabetes. 2014 Jun;63 (6) :2051-62.