Befetupitant
Befetupitant is a high-affinity, nonpeptide, competitive tachykinin 1 receptor (NK1R) antagonist.
Product Specifications
CAS Number
290296-68-3
Product Name Alternative
Ro67-5930
UNSPSC
12352005
Target
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Befetupitant.html
Solubility
10 mM in DMSO
Smiles
CN(C(C(C)(C)C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)=O)C2=CN=C(N3CCOCC3)C=C2C4=C(C)C=CC=C4
Molecular Formula
C29H29F6N3O2
Molecular Weight
565.55
References & Citations
[1]Bignami F, et al. NK1 receptor antagonists as a new treatment for corneal neovascularization. Invest Ophthalmol Vis Sci. 2014 Sep 16;55 (10) :6783-94.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NK1R
Available Sizes
Frequently Asked Questions
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