RBC8
RBC8 is a selective and allosteric RALA and RALB inhibitor. RBC8 stabilizes the inactive GDP-bound state of Ral, preventing its activation. RBC8 promotes the phosphorylation of proteins related to the MAPK/JNK pathway. RBC8 has the activity of inhibiting tumor cell proliferation, migration and invasion. RBC8 is used in the study of various cancers such as lung cancer, gastric cancer, and multiple myeloma[1][2][3].
Product Specifications
CAS Number
361185-42-4
UNSPSC
12352005
Hazard Statement
H302
Target
JNK; p38 MAPK; Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/RBC8.html
Purity
98.0
Solubility
DMSO : ≥ 40 mg/mL
Smiles
N#CC(C1C2=CC(OC)=CC=C2OC)=C(N)OC3=C1C(C4=CC=C5C=CC=CC5=C4)=NN3
Molecular Formula
C25H20N4O3
Molecular Weight
424.45
Precautions
H302
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
TAF9B CRISPRa sgRNA lentivector (set of three targets)(Rat)
SV2C sgRNA CRISPR Lentivector (Human) (Target 3)
Goat Anti-Mouse IgG1 Antibody (AcalephFluor790)