UNC-2170
UNC-2170 is a functionally active, fragment-like ligand for 53BP1 (IC50=29 µM; Kd=22 µM) . UNC-2170 shows at least 17-fold selectivity for 53BP1 as compared to nine other methyl-lysine (Kme) reader proteins. 53BP1 is a Kme binding protein that plays a central role in DNA Damage Repair (DDR) pathways and is recruited to sites of double-strand breaks (DSB) [1].
Product Specifications
CAS Number
1648707-58-7
Product Name Alternative
PQQ (disodium salt); Methoxatin (disodium salt),PQQ; Methoxatin
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/unc-2170.html
Purity
98.84
Solubility
DMSO : 100 mg/mL (ultrasonic) |Methanol : 125 mg/mL (ultrasonic)
Smiles
O=C(NCCCNC(C)(C)C)C1=CC=CC(Br)=C1
Molecular Formula
C14H21BrN2O
Molecular Weight
313.23
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CD63 (Late Endosomes Marker) (LAMP3/2790), CF740 conjugate, 0.1mg/mL
