D-Pinitol

D-pinitol (3-O-Methyl-D-chiro-inositol) is a natural compound presented in several plants, like Pinaceae and Leguminosae plants. D-pinitol exerts hypoglycemic activity and protective effects in the cardiovascular system[1][2]. D-pinitol has antiviral and larvicidal activities[3].

Product Specifications

CAS Number

[10284-63-6]

Product Name Alternative

3-O-Methyl-D-chiro-inositol

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H332, H335

Target

Influenza Virus

Type

Natural Products

Related Pathways

Anti-infection

Applications

Neuroscience-Neuromodulation

Field of Research

Infection; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/d-pinitol.html

Concentration

10mM

Purity

99.79

Solubility

DMSO : 116.67 mg/mL (ultrasonic)

Smiles

O[C@@H]1[C@@H]([C@H]([C@@H]([C@H]([C@H]1O)O)O)OC)O

Molecular Formula

C7H14O6

Molecular Weight

194.18

Precautions

H302, H315, H319, H332, H335

References & Citations

[1]Gao Y, et al. Effects of D-Pinitol on Insulin Resistance through the PI3K/Akt Signaling Pathway in Type 2Diabetes Mellitus Rats. J Agric Food Chem. 2015 Jul 8;63 (26) :6019-26.|[2]Moreira LN, et al. Activation of eNOS by D-pinitol Induces an Endothelium-Dependent Vasodilatation in MouseMesenteric Artery. Front Pharmacol. 2018 May 22;9:528.|[3]Rengarajan T, et al. D-pinitol promotes apoptosis in MCF-7 cells via induction of p53 and Bax and inhibition of Bcl-2 and NF-κB. Asian Pac J Cancer Prev. 2014;15 (4) :1757-62.|[4]Sethi G, et al. Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis. Mol Cancer Ther. 2008 Jun;7 (6) :1604-14.