R1663
R1663 is a factor Xa inhibitor with anticoagulant activity. R1663 does not affect bleeding time. The pharmacodynamic effects (such as inhibition of thrombin generation) and plasma concentrations of R1663 are dose-dependent. R1663 prolongs clotting time in a concentration-dependent manner and inhibits the peak height of thrombin generation and endogenous thrombin potential[1].
Product Specifications
CAS Number
[865451-66-7]
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/r1663.html
Smiles
O=C([C@H]1CN(CC(F)F)C[C@@H]1C(NC2=CC=C(N3C=CC=CC3=O)C=C2F)=O)NC4=NC=C(Cl)C=C4
Molecular Formula
C24H21ClF3N5O3
Molecular Weight
519.90
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
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