(S) - (-) -Propranolol (hydrochloride)

(S) - (-) -Propranolol hydrochloride is a β-adrenergic receptor antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively. (S) - (-) -Propranolol hydrochloride the active enantiomer of propranolol and can be s used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[2].

Product Specifications

CAS Number

[4199-10-4]

UNSPSC

12352005

Hazard Statement

H302+H312+H332

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/s-minus-propranolol-hydrochloride.html

Concentration

10mM

Purity

99.97

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : ≥ 10 mg/mL

Smiles

O[C@H](COC1=C2C=CC=CC2=CC=C1)CNC(C)C.[H]Cl

Molecular Formula

C16H22ClNO2

Molecular Weight

295.81

Precautions

H302+H312+H332

References & Citations

[1]Jillian G Baker , et al. The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors. Br J Pharmacol. 2005 Feb;144 (3) :317-22.