N-Myristoyl-Lys-Arg-Thr-Leu-Arg
Product Specifications
UNSPSC Description
N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a protein kinase C (PKC) inhibitor with an IC50 value of 75 μM. N-Myristoyl-Lys-Arg-Thr-Leu-Arg inhibits IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat[1].
Target Antigen
PKC
Type
Peptides
Related Pathways
Epigenetics;TGF-beta/Smad
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/n-myristoyl-lys-arg-thr-leu-arg.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)[C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC(CCCCCCCCCCCCC)=O)=O
Molecular Weight
883.18
References & Citations
[1]Ioannides CG, et, al. Inhibition of IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat by a novel peptide inhibitor of protein kinase C. Cell Immunol. 1990 Nov;131(1):242-52.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P3083/N-Myristoyl-Lys-Arg-Thr-Leu-Arg-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P3083/
Clinical Information
No Development Reported
CAS Number
125678-68-4
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