FLI-06
Product Specifications
UNSPSC Description
FLI-06 is an inhibitor of Notch signaling with an EC50 of 2.3 μM.
Target Antigen
Notch
Type
Reference compound
Related Pathways
Neuronal Signaling;Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/FLI-06.html
Solubility
DMSO : ≥ 38 mg/mL
Smiles
O=C(C1=C(C)NC2=C(C(CC(C)(C)C2)=O)C1C3=CC=C([N+]([O-])=O)C=C3)OC4CCCCC4
Molecular Weight
438.52
References & Citations
[1]Kramer A, et al. Small molecules intercept Notch signaling and the early secretory pathway. Nat Chem Biol. 2013 Nov;9(11):731-8.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-15860/FLI-06-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15860/FLI-06-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
313967-18-9
Available Sizes
Curated Selection
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