DSPE-PEG-DBCO, MW 2000

DSPE-PEG-DBCO, MW 2000 is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery[1]. DSPE-PEG-DBCO, MW 2000 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Product Specifications

CAS Number

[1895854-56-4]

Product Name Alternative

DSPE-PEG (2000) -DBCO

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Liposome

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dspe-peg-dbco-mw-2000.html

Purity

99.90

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CCCCCCCCCCCCCCCCCC(OC[C@](OC(CCCCCCCCCCCCCCCCC)=O)([H])COP(O)(OCCNC(OCCNC(CCCCC(N1C(C=CC=C2)=C2C#CC(C=CC=C3)=C3C1)=O)=O)=O)=O)=O.[n]

Molecular Formula

(C2H4O) nC43H86NO9P

Molecular Weight

2000 (Average)

Precautions

H302, H315, H319, H335

References & Citations

[1]Oude Blenke E, et al. Strategies for the Activation and Release of the Membranolytic Peptide Melittin from Liposomes Using Endosomal pH as a Trigger. Bioconjug Chem. 2017 Feb 15;28 (2) :574-582.