Pyridoxine-d5

Pyridoxine-d5 (Pyridoxol-d5) is a deuterium labeled Pyridoxine (HY-B1328) . Pyridoxine (Pyridoxol) is a pyridine derivative. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.

Product Specifications

CAS Number

[688302-31-0]

Product Name Alternative

Pyridoxol-d5

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Isotope-Labeled Compounds; Keap1-Nrf2

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; NF-κB; Others

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Purity

95.0

Solubility

DMSO : 100 mg/mL (ultrasonic; warming)

Smiles

OCC1=C(O)C(C([2H])([2H])[2H])=NC=C1C([2H])([2H])O

Molecular Formula

C8H6D5NO3

Molecular Weight

174.21

Precautions

H302, H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-246.|[2]Li C, et al. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway. Cell Mol Biol (Noisy-le-grand) . 2018 Jul 30;64 (10) :119-124.