Pyridoxine-d5
Pyridoxine-d5 (Pyridoxol-d5) is a deuterium labeled Pyridoxine. Pyridoxine (Pyridoxol) is a pyridine derivative. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
Product Specifications
CAS Number
688302-31-0
Product Name Alternative
Pyridoxol-d5
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Isotope-Labeled Compounds; Keap1-Nrf2
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; NF-κB; Others
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Purity
95.0
Solubility
DMSO : 100 mg/mL (ultrasonic; warming)
Smiles
OCC1=C(O)C(C([2H])([2H])[2H])=NC=C1C([2H])([2H])O
Molecular Formula
C8H6D5NO3
Molecular Weight
174.21
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-246.|[2]Li C, et al. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway. Cell Mol Biol (Noisy-le-grand) . 2018 Jul 30;64 (10) :119-124.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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