CPT-157633
CPT-157633, a difluoro-phosphonomethyl phenylalanine derivative, and is a PTP1B inhibitor. CPT-157633 prevents binge drinking-induced glucose intolerance[1].
Product Specifications
CAS Number
888213-72-7
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cpt-157633.html
Concentration
10mM
Purity
99.14
Solubility
DMSO : 200 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
FC(C1=CC=C(C[C@H](NS(=O)(C)=O)C(NC)=O)C=C1Br)(P(O)(O)=O)F
Molecular Formula
C12H16BrF2N2O6PS
Molecular Weight
465.20
References & Citations
[1]Lindtner C, et, al. Binge drinking induces whole-body insulin resistance by impairing hypothalamic insulin action. Sci Transl Med. 2013 Jan 30;5 (170) :170ra14.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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