Nω-Propyl-L-arginine
Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS) [1][2].
Product Specifications
CAS Number
137361-05-8
Product Name Alternative
N-omega-Propyl-L-arginine
UNSPSC
12352211
Hazard Statement
H319
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nω-propyl-l-arginine.html
Purity
98.62
Solubility
H2O : ≥ 100 mg/mL
Smiles
N=C(NCCC)NCCC[C@H](N)C(O)=O
Molecular Formula
C9H20N4O2
Molecular Weight
216.28
Precautions
H319
References & Citations
[1]Zhang HQ, et al. Potent and selective inhibition of neuronal nitric oxide synthase by N omega-propyl-L-arginine. J Med Chem. 1997 Nov 21;40 (24) :3869-70.|[2]Klamer D, et al. The neuronal selective nitric oxide synthase inhibitor, Nomega-propyl-L-arginine, blocks the effects of phencyclidine on prepulse inhibition and locomotor activity in mice. Eur J Pharmacol. 2004 Oct 25;503 (1-3) :103-7.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NNOS
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC400177-500 1x 500 µL
CD50 (ICAM-3) (101-1D2), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC740745-500 1x 500 µL
CD45 / LCA (2B11 + PD7/26), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC682755-100 1x 100 µL
Adipophilin / Perilipin-2 (Marker of Lipid Accumulation) (ADFP/2755R), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC681825-100 1x 100 µL
Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details