DNase I, Bovine pancreas

DNase I (EC 3.1.21.1) is an enzyme that degrade DNA, it plays a key role in the cleavage of extracellular DNA is crucial for limiting the inflammatory response and maintaining homeostasis. Exogenous deoxyribonuclease shows beneficial effects in inflammatory diseases and cancer[1].

Product Specifications

CAS Number

[9003-98-9]

Product Name Alternative

DNase

UNSPSC

12352204

Hazard Statement

H302, H315, H319, H335

Target

Others

Type

Enzyme

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/dnase-i-bovine-pancreas.html

Solubility

H2O : 4 mg/mL

Smiles

[DNaseI,Bovinepancreas]

Precautions

H302, H315, H319, H335

References & Citations

[1]Lauková L, et al. Deoxyribonucleases and Their Applications in Biomedicine. Biomolecules. 2020 Jul 11;10 (7) :1036.|[2]Sugihara S, et al. Deoxyribonuclease treatment prevents blood-borne liver metastasis of cutaneously transplanted tumour cells in mice. Br J Cancer. 1993 Jan;67 (1) :66-70.

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20°C for 2 years

Scientific Category

Enzyme

Clinical Information

Launched

Citation 01

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