16α-Hydroxytrametenolic acid

16α-Hydroxytrametenolic acid, a natural triterpene, is a potential retinoid X receptor (RXR) selective agonist[1].

Product Specifications

CAS Number

[176390-68-4]

UNSPSC

12352211

Target

RAR/RXR

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/16α-hydroxytrametenolic-acid.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

C[C@]12[C@@]([C@@]([C@@H](C1)O)([H])[C@H](C(O)=O)CC/C=C(C)\C)(CCC3=C2CC[C@]4([H])[C@@]3(CC[C@@H](C4(C)C)O)C)C

Molecular Formula

C30H48O4

Molecular Weight

472.70

References & Citations

[1]Hui Xu, et al. Triterpenes from Poria cocos are revealed as potential retinoid X receptor selective agonists based on cell and in silico evidence. Chem Biol Drug Des. 2020 May;95 (5) :493-502.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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