Camphor

Camphor ((±) -Camphor) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative. However, Camphor is poisonous when ingested. Antiviral, antitussive, and anticancer activities[1]. Camphor is a TRPV3 agonist[2].

Product Specifications

CAS Number

[76-22-2]

Product Name Alternative

(±) -Camphor

UNSPSC

12352211

Hazard Statement

H228, H315, H318, H332, H371, H401, H411

Target

Influenza Virus; TRP Channel

Type

Natural Products

Related Pathways

Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Cancer-Kinase/protease

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Camphor.html

Purity

99.47

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C(C2(C)C)(C)CCC2C1

Molecular Formula

C10H16O

Molecular Weight

152.24

Precautions

H228, H315, H318, H332, H371, H401, H411

References & Citations

[1]Chen W, et al. Camphor--a fumigant during the Black Death and a coveted fragrant wood in ancient Egypt and Babylon--a review. Molecules. 2013 May 10;18 (5) :5434-54.|[2]Billen B, et al. Different ligands of the TRPV3 cation channel cause distinct conformational changes as revealedby intrinsic tryptophan fluorescence quenching. J Biol Chem. 2015 May 15;290 (20) :12964-74.|[3]Tran TA, et al. Camphor Induces Proliferative and Anti-senescence Activities in Human Primary Dermal Fibroblasts and Inhibits UV-Induced Wrinkle Formation in Mouse Skin. Phytother Res. 2015 Dec;29 (12) :1917-25.