PROTAC EGFR degrader 7 (diTFA)
Product Specifications
UNSPSC Description
Target Antigen
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/protac-egfr-degrader-7-ditfa.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C#CCN(CCN(C1=CC(OC)=C(C=C1NC(C=C)=O)NC2=NC(C3=CN(C4=CC=CC=C34)C)=CC=N2)C)CCCC(NC5=C6CN(C(C6=CC=C5)=O)C7CCC(NC7=O)=O)=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O
Molecular Weight
1064.98
References & Citations
[1]Zhang W, et al. Discovery of highly potent and selective CRBN-recruiting EGFRL858R/T790M degraders in vivo. Eur J Med Chem. 2022 Aug 5;238:114509.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147858A/PROTAC-EGFR-degrader-7-diTFA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147858A/PROTAC-EGFR-degrader-7-diTFA-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
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