PROTAC EGFR degrader 7 (diTFA)
Product Specifications
UNSPSC Description
Target Antigen
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/protac-egfr-degrader-7-ditfa.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C#CCN(CCN(C1=CC(OC)=C(C=C1NC(C=C)=O)NC2=NC(C3=CN(C4=CC=CC=C34)C)=CC=N2)C)CCCC(NC5=C6CN(C(C6=CC=C5)=O)C7CCC(NC7=O)=O)=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O
Molecular Weight
1064.98
References & Citations
[1]Zhang W, et al. Discovery of highly potent and selective CRBN-recruiting EGFRL858R/T790M degraders in vivo. Eur J Med Chem. 2022 Aug 5;238:114509.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147858A/PROTAC-EGFR-degrader-7-diTFA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147858A/PROTAC-EGFR-degrader-7-diTFA-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Recombinant Burkholderia phymatum Imidazole glycerol phosphate synthase subunit HisF (hisF)
Recombinant Burkholderia phymatum Imidazole glycerol phosphate synthase subunit HisF (hisF)
Recombinant Burkholderia phymatum Imidazole glycerol phosphate synthase subunit HisF (hisF)
Recombinant Burkholderia phymatum Imidazole glycerol phosphate synthase subunit HisF (hisF)
Recombinant Burkholderia phymatum Imidazole glycerol phosphate synthase subunit HisF (hisF)