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NCGC00247743

NCGC00247743 is a histone lysine demethylase KDM4 inhibitor.

Product Specifications

CAS Number

1435192-04-3

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Histone Demethylase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/NCGC00247743.html

Concentration

10mM

Purity

99.38

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

OC1=C(N=CC=C2)C2=CC(C3=CC(C(NCCCCCCN(C)C)=O)=CC=C3)=C1

Molecular Formula

C24H29N3O2

Molecular Weight

391.51

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Duan L, et al. KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes. Chem Biol. 2015 Sep 17;22 (9) :1185-96.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

KDM4

Available Sizes

Frequently Asked Questions

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