NCGC00247743
NCGC00247743 is a histone lysine demethylase KDM4 inhibitor.
Product Specifications
CAS Number
[1435192-04-3]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/NCGC00247743.html
Concentration
10mM
Purity
99.38
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
OC1=C(N=CC=C2)C2=CC(C3=CC(C(NCCCCCCN(C)C)=O)=CC=C3)=C1
Molecular Formula
C24H29N3O2
Molecular Weight
391.51
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Duan L, et al. KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes. Chem Biol. 2015 Sep 17;22 (9) :1185-96.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KDM4
Available Sizes
Curated Selection
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