Endothelin-3, human, mouse, rabbit, rat (TFA)

Endothelin-3, human, mouse, rabbit, rat TFA is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.

Product Specifications

Product Name Alternative

Endothelin 3 (Rat, Human) (TFA)

UNSPSC

12352209

Target

Endothelin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/endothelin-3-human-mouse-rabbit-rat-tfa.html

Purity

99.96

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H]([C@H](O)C)C(N[C@@H](CS)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@@H](CS)C(N[C@@H](C(C)C)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](CC4=CC=C(C=C4)O)C(N[C@@H](CS)C(N[C@@H](CC5=CNC=N5)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC6=CNC7=CC=CC=C67)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CS)N.OC(C(F)(F)F)=O.[x]

Molecular Formula

C123H169F3N26O35S4.xC2HF3O2

Molecular Weight

2757.07 (free base)

References & Citations

[1]Skovsted GF, et al. Endothelin-1 and Endothelin-3 Regulate Endothelin Receptor Expression in Rat Coronary Arteries. Basic Clin Pharmacol Toxicol. 2015 Nov;117 (5) :297-305.