DIBAC-GGFG-NH2CH2-Dxd
DIBAC-GGFG-NH2CH2-Dxd (compound LP4), a Camptothecin derivative, is a linker-payload of protein-agent conjugates[1]. Dxd (HY-13631D) can be used as a payload for the antibody-coupling drug ADC (DS-8201a).DIBAC-GGFG-NH2CH2-Dxd is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups[1][2].
Product Specifications
CAS Number
2758875-01-1
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dibac-ggfg-nh2ch2-dxd.html
Purity
98.57
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
Molecular Formula
C61H58FN9O12
Molecular Weight
1128.16
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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