PTPN2 ligand 1
PTPN2 ligand 1 is a PROTAC target protein ligand (Ligands for Target Protein for PROTAC) . PTPN2 ligand 1 can be used to synthesize PVD-06 (HY-149760) [1].
Product Specifications
CAS Number
[3032975-34-8]
UNSPSC
12352101
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ptpn2-ligand-1.html
Smiles
O=C(CN1N=CC(C2=CC=C3C=C(O)C(N4CC(NS4(=O)=O)=O)=C(F)C3=C2)=C1)O
Molecular Formula
C17H13FN4O6S
Molecular Weight
420.37
References & Citations
[1]Hu L, et al. Discovery of PVD-06 as a Subtype-Selective and Efficient PTPN2 Degrader. J Med Chem. 2023 Nov 23;66 (22) :15269-15287.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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