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P62, SQSTM1 Polyclonal Antibody

<strong>P62,SQSTM1 Polyclonal Antibody</strong>_x000D_ <strong>Catalog number:</strong> B2017130_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µL_x000D_ <strong>Molecular Weight or Concentration:</strong> 48 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20‚ÑÉ_x000D_ <strong>Keywords:</strong> P62,SQSTM1 Polyclonal Antibody_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Kuusisto E, Kauppinen T, Alafuzoff I. Use of p62/SQSTM1 antibodies for neuropathological diagnosis Neuropathol Appl Neurobiol. 2008 Apr;34(2):169-80._x000D_ 2: Lamark T, Svenning S, Johansen T. Regulation of selective autophagy: the p62/SQSTM1 paradigm Essays Biochem. 2017 Dec 12;61(6):609-624._x000D_ 3: Jeong SJ, Zhang X, Rodriguez-Velez A, Evans TD, Razani B. p62/SQSTM1 and Selective Autophagy in Cardiometabolic Diseases Antioxid Redox Signal. 2019 Aug 20;31(6):458-471._x000D_ 4: Bj√∏rk√∏y G, Lamark T, Pankiv S, √òvervatn A, Brech A, Johansen T. Monitoring autophagic degradation of p62/SQSTM1 Methods Enzymol. 2009;452:181-97._x000D_ 5: Kumar AV, Mills J, Lapierre LR. Selective Autophagy Receptor p62/SQSTM1, a Pivotal Player in Stress and Aging Front Cell Dev Biol. 2022 Feb 14;10:793328._x000D_ 6: Shi Q, Jin X, Zhang P, Li Q, Lv Z, Ding Y, He H, Wang Y, He Y, Zhao X, Zhao SM, Li Y, Gao K, Wang C. SPOP mutations promote p62/SQSTM1-dependent autophagy and Nrf2 activation in prostate cancer Cell Death Differ. 2022 Jun;29(6):1228-1239._x000D_ 7: Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, √òvervatn A, Bj√∏rk√∏y G, Johansen T. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy J Biol Chem. 2007 Aug 17;282(33):24131-45._x000D_ 8: S√°nchez-Mart√≠n P, Saito T, Komatsu M. p62/SQSTM1: 'Jack of all trades' in health and cancer FEBS J. 2019 Jan;286(1):8-23._x000D_ 9: Gallagher ER, Holzbaur ELF. The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy Cell Rep. 2023 Feb 28;42(2):112037._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/35455030">10: Sabbieti MG, Marchegiani A, Sufianov AA, Gabai VL, Shneider A, Agas D. P62/SQSTM1 beyond Autophagy: Physiological Role and Therapeutic Applications in Laboratory and Domestic Animals Life (Basel). 2022 Apr 6;12(4):539. </a>_x000D_ _x000D_ <strong>Products Related to P62,SQSTM1 Polyclonal Antibody can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>

Product Specifications

CAS Number

9007-83-4

Short Description

Catalog Number: B2017130 (50 µL)

Weight

0.15

Length

2

Width

0.5

Height

0.5

Frequently Asked Questions

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